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· huanglongbing (hlb) is a devastating citrus disease. · deep learning has advanced the design of static protein structures, but the controlled conformational changes that are hallmarks of natural signaling proteins have … In this work, we report an hlb resistance regulatory circuit in citrus composed of an e3 ubiquitin ligase, pub21, and its … A neuromorphic e-skin system simultaneously emulates closed-loop sensory encoding and mechanical softness of natural skin. · the gut microbiota is known to be associated with a variety of human metabolic diseases, including metabolic dysfunction–associated steatohepatitis (mash). In this work, we fabricated a subretinal nanoprosthesis using … · present vision restoration technologies have substantial constraints that limit their application in the clinical setting. · science is the leading multidisciplinary, international journal of peer-reviewed research including analysis and news coverage of breakthroughs and policy. Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life … · toxic metal pollution is ubiquitous in soils, yet its worldwide distribution is unknown. · we present a bulk nanocrystalline copper alloy that can operate at near-melting temperatures with minimal coarsening and creep deformation. The thermal stability of the cu … We analyzed a global database of soil pollution by arsenic, cadmium, cobalt, … · science/aaas peer-reviewed journals deliver impactful research, daily news, expert commentary, and career resources.