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Important safety information what is the most important information i should know about zoloft? Find answers to your questions about depression and treatment with zoloft® (sertraline hcl). See risks & benefits. Stopping zoloft may cause serious symptoms, including anxiety, irritability, high or low mood, feeling … Before taking zoloft, tell your healthcare provider about all your medical conditions and all the medicines you take, including … Zoloft is a prescription medication for the treatment, in adults, of major depressive disorder (mdd), obsessive-compulsive disorder (ocd), panic disorder, … Zoloft may cause serious … Do not stop zoloft without first talking to your healthcare provider.