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· osteoclast progenitors fuse together on the bone surfaces but are primarily found in bone marrow, where they derive … · osteoblasts and osteoclasts are cells that work together to form new bones and break down old or damaged bone tissue. · at the site of bone resorption, an active osteoclast develops a specialized structure called the ruffled border, which … Structure tartrate resistant acid phosphatase positive osteoclast in cell culture illustrated cross-section of an activated osteoclast an … The osteoclast, which is the sole bone-resorbing cell, is a unique polykaryon whose activity, in the context of the osteoblast, …