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In this work, we report an hlb resistance regulatory circuit in citrus composed of an e3 ubiquitin ligase, pub21, and its substrate, the myc2 transcription factor, which regulates jasmonate-mediated. · toxic metal pollution is ubiquitous in soils, yet its worldwide distribution is unknown. · we present a bulk nanocrystalline copper alloy that can operate at near-melting temperatures with minimal coarsening and creep deformation. Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. · science is the leading multidisciplinary, international journal of peer-reviewed research including analysis and news coverage of breakthroughs and policy. · science/aaas peer-reviewed journals deliver impactful research, daily news, expert commentary, and career resources. We analyzed a global database of soil pollution by arsenic, cadmium, cobalt, chromium, copper, nickel, and lead at 796,084 sampling points from 1493 regional studies. · huanglongbing (hlb) is a devastating citrus disease. · present vision restoration technologies have substantial constraints that limit their application in the clinical setting. · a drug with a novel mechanism protects people against the aids virus for 6 months. Crispr-associated transposases (casts) catalyze rna-guided. It could speed the end of the epidemic—if those who need it most get access In this work, we fabricated a subretinal nanoprosthesis using tellurium nanowire networks (tenwns) that converts light of both the. Using eight glacier models, we simulated global glacier evolution over multicentennial timescales, allowing glaciers to equilibrate. · glaciers adapt slowly to changing climatic conditions, with long-term implications for sea-level rise and water supply. The thermal stability of the cu-3ta-0. 5li atomic % (at %) alloy is attributed to coherent, ordered l12 cu3li. A neuromorphic e-skin system simultaneously emulates closed-loop sensory encoding and mechanical softness of natural skin.